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West Florida Hospital

Medications for Chlamydia

The content below is part of the “Health Library” and is not indicative of services available at the facility.

Prescription Medications

Chlamydia is treated with antibiotics. It is important to finish all antibiotics as prescribed, even if you are feeling better. Not doing so risks reinfection.

First-line antibiotics include:

  • Azithromycin
  • Doxycycline

Other antibiotics include:

  • Amoxicillin
  • Erythromycin
  • Levofloxacin
  • Ofloxacin


This antibiotic is effective with a single dose. If you have liver or kidney disease, this medication should be use with caution. This antibiotic is the preferred medication for use in pregnant women.

Side effects may include:


This antibiotic is usually given for 7 days. It is just as effective as a single dose of azithromycin. It should not be used in children less than 8 years old or during pregnancy.

Side effects may include:

  • Nausea or vomiting
  • Sensitivity to sunlight
  • Diarrhea
  • Decreased appetite

Other antibiotics

  • Amoxicillin
  • Erythromycin
  • Levofloxacin
  • Ofloxacin

These antibiotics are usually given for 7 days.

Side effects may include:

  • Nausea or vomiting
  • Diarrhea
  • Constipation
  • Rash
  • Cramping, loss of appetite (erythromycin)
  • Headache, lightheadedness, insomnia (levofloxacin, ofloxacin)

Revision Information

  • Reviewer: EBSCO Medical Review Board Marcie L. Sidman, MD
  • Review Date: 03/2017 -
  • Update Date: 03/15/2015 -
  • Chlamydia—CDC fact sheet. Centers for Disease Control and Prevention website. Available at: Updated September 24, 2015. Accessed March 14, 2016.

  • Chlamydia genital infection. EBSCO DynaMed Plus website. Available at: Updated February 15, 2016. Accessed October 6, 2016.

  • Mishori R, McClaskey, EL, et al. Chlamydia trachomatis infections: Screening, diagnosis, and management. Am Fam Physician. 2012;86(12):1127-1132.

  • Workowski KA, Berman S, Centers for Disease Control and Prevention. Sexually Transmitted Diseases Treatment Guidelines, 2010. MMWR. 2010;59(No. RR-12):1-110.