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Depression and Nocturia May Be Bidirectionally Linked

Depression and Nocturia May Be Bidirectionally Linked

Depression risk greater for men with nocturia than for women with nocturia

FRIDAY, Aug. 23 (HealthDay News) -- There may be a bidirectional association between depression and nocturia, according to a review published in the September issue of The Journal of Urology.

Benjamin N. Breyer, M.D., from the University of California in San Francisco, and colleagues conducted a literature review to identify abstracts and original, review, and editorial articles on nocturia and mood disorders, specifically depression and anxiety.

The researchers observed a strong association between nocturia and depression/anxiety based on cross-sectional (level 3) data. A single prospective study found a unidirectional relationship with depression leading to nocturia. Nocturia posed a greater risk for depression in men than in women. The effect of serotonin reuptake inhibitors on nocturia demonstrated conflicting results.

"Practicing clinicians should consider administering a brief self-administered scale to assess for depression in patients with nocturia," the authors write.

Several authors disclosed financial ties to the pharmaceutical industry.

Abstract (http://www.jurology.com/article/S0022-5347(13)04349-8/abstract )Full Text (subscription or payment may be required) (http://www.jurology.com/article/S0022-5347(13)04349-8/fulltext )