Polycystic Ovary Syndrome
(PCOS; Stein Leventhal Syndrome; Polyfollicular Ovarian Appearance; Hyperandrogenic Anovulation; Polycystic Ovarian Disease; PCO; PCOD)
|Ovary and Fallopian Tube|
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- Family members with PCOS
- Irregular menstrual cycles
- Sedentary lifestyle
- Amenorrhea—irregular menstrual periods or no menstrual period
- Dark patches of skin on neck, groin, and arm pit
- Hair loss
- Type 2 diabetes
- High cholesterol
- High blood pressure
- Metabolic syndrome—A condition is marked by elevated blood pressure, cholesterol, blood glucose, and body weight. Excess weight centered around the midsection is of particular concern.
- Heart disease
- Endometrial hyperplasia—A precancerous condition marked by overgrowth and thickening of uterine lining.
- Endometrial cancer
- Managing symptoms
- Weight loss if overweight
- Healthy eating
- Medications to improve insulin resistance, glucose intolerance, and prediabetes management
- Oral contraceptive
Inducing ovulation (if you want to get pregnant)
- Metformin or clomiphene citrate
- Advanced reproductive technologies
- Preventing complications
- Anti-androgenic medications for blocking future hirsutism
The American Congress of Obstetricians and Gynecologists http://www.acog.org
Polycystic Ovarian Syndrome Association http://www.pcosupport.org
The Society of Obstetricians and Gynaecologists of Canada http://www.sogc.org
Women's Health Matters http://www.womenshealthmatters.ca
ACOG Committee on Practice Bulletins—Gynecology. ACOG Practice Bulletin No. 108: Polycystic ovary syndrome. Obstet Gynecol. 2009;114(4):936-949. Reaffirmed 2013.
Baillargeon JP. Use of insulin sensitizers in polycystic ovarian syndrome. Curr Opin Invetig Drugs. 2005:6(10):1012-1022.
Glintborg D, Altinok ML, Mumm H, et al. Body composition is improved during 12 months' treatment with metformin alone or combined with oral contraceptives compared with treatment with oral contraceptives in polycystic ovary syndrome. J Clin Endocrinol Metab. 2014;99(7):2584-2591.
Li XJ, Yu YX, Liu CQ, et al. Metformin vs thiazolidinediones for treatment of clinical, hormonal and metabolic characteristics of polycystic ovary syndrome: A meta-analysis. Clin Endocrinol (Oxf). 2011;74(3):332-339.
Polycystic ovary syndrome. American Academy of Family Physicians Family Doctor website. Available at: http://familydoctor.org/familydoctor/en/diseases-conditions/polycystic-ovary-syndrome.html. Updated August 2010. Accessed July 26, 2013.
Polycystic ovary syndrome. EBSCO DynaMed website. Available at: http://www.ebscohost.com/dynamed. Updated June 17, 2013. Accessed July 26, 2013.
Polycystic ovary syndrome (PCOS). Endocrine Society Hormone Health Network website. Available at: http://www.hormone.org/diseases-and-conditions/womens-health/polycystic-ovary-syndrome. Updated May 2013. Accessed July 26, 2013.
Stadmauer L, Oehninger S. Management of infertility in women with polycystic ovary syndrome: A practical guide. Treat Endocrinology. 2005;4(5):279-292.
- Reviewer: Andrea Chisholm, MD
- Review Date: 05/2015 -
- Update Date: 05/11/2013 -